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Homology modeling and docking studies of Comamonas testosteroni B-356 biphenyl-2, 3-dioxygenase involved in degradation of polychlorinated biphenyls
Indian Institute of Toxicology Research
The three-dimensional model of a-subunit of Biphenyl dioxygenase (BphA) from Comamonas testosteroni B-356 has been constructed. The kinetic parameters of biphenyl compounds were well matched with the docking results. The binding properties of these biphenyl compounds along with identification of critical active site residues could be used for further site-directed mutagenesis experiments in order to identify their role in activity and substrate specificity.
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Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy
The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.
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Postdoctoral Research Associate
Northeastern University
The Center for Drug Discovery at Northeastern University is dedicated to designing and discovering novel medications, developing technologies, and training scientists in the multidisciplinary field of drug discovery. We are recruiting a Postdoctoral Research Associate with expertise in protein-based mass spectrometry and /or proteomics.
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Product Manager - Techne, Stone, Staffordshire
Bibby Scientific
Bibby Scientific Ltd is one of the world’s leading manufacturers of Laboratory bench-top scientific equipment. For more information about the company, please visit their website (www.bibby-scientific.com).
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Assistant/Associate Professors
Chinese University of Hong Kong
The newly established School of Biomedical Sciences, Stem Cell and Regeneration theme is actively looking for stem cell biologist over the next 2 years.
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Macromolecular X-ray Crystallgrapher
Xtal Biostructures
Ph.D. Protein Crystallographer: We seek an experienced crystallographer with post-doctoral experience to participate in a number of our diverse structural biology activities.
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Marketing Communications Specialist Position in San Jose, CA
Thermo Fisher Scientific
This position, based in San Jose, CA within the SID Division, will manage promotion of Thermo Scientific mass spectrometry products and services.
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St. Jude Children's Research Hospital has an opening for a Senior Research Technologist (Job Number 18046)
St Judes Research Hospital
St. Jude Children's Research Hospital, located in Memphis, Tennessee, is a premier center for research and treatment of potentially fatal childhood diseases, including cancer and certain blood, genetic, and immunodeficiency disorders. The hospital's mission is to advance cures, and means of prevention, for pediatric catastrophic diseases through research and treatment.
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2nd Annual Predictive Toxicology Conference 24-25 February 2010
24 February 2010 - 25 February 2010
Pharma IQ is delighted to announce the dates for the 2nd Annual Predictive Toxicology Conference taking place in London on the 24th-25th February 2010. Predictive Toxicology is a constantly evolving area of R&D, helping to reduce costs and increase efficiency of drug development through ever more innovative technologies to ultimately ensure that pipeline compounds pass legislation and become safe, profit-making drugs.
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ADMET Europe, Munich, Germany
08 April 2010 - 09 April 2010
Select Biosciences is pleased to announce its 3rd annual ADMET Europe conference. Topics to be covered will include cutting edge discoveries in microdosing such as advances in the use of Accelerator Mass Spectrometry (AMS) to deliver microdoses, as well as advances in setups of in-vivo, in-vitro and in-silico techniques.
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Pharma Outsourcing Congress, Munich, Germany
08 April 2010 - 09 April 2010
Due to its continuing success, we are pleased to announce our 2nd Annual PharmaOutsourcing conference. Included will be a host of topics designed to give you new ideas and approaches for your outsourcing needs, as well as looking at implementing and managing clinical trials in Europe and Asia.
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SBS 16th Annual Conference & Exhibition, Phoenix, Arizona, USA
11 April 2010 - 15 April 2010
Advancing the Science of Drug Discovery: More than 2,000 scientists, innovators, researchers and industry analysts from around the world will converge in Phoenix to learn about the latest trends and basic and applied research that are transforming the way new pharmaceuticals are developed.
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Toxicity Screening 2009 Market Report
Published February 2009
This is the latest and most up-to-date Toxicity Screening Market Analysis Report from Select Biosciences. This comprehensive report provides a qualitative and quantitative analysis of the toxicity screening space, market metrics, and thorough bottom-up based market trends obtained via detailed market surveys administered by Select Biosciences to a worldwide industry participant pool.
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TR-FRET Based Assay Trends 2007
Published December 2007
This market report summarizes the results of HTStec’s global pharma and biotech web-based benchmarking survey on TR-FRET based assays and reagents carried out in December 2007.
The study was initiated to comprehensively document current practices, requirements and future trends for TR-FRET based assay reagent technologies. The questions were aimed at providing vendors with updated information on the use of theses assays and direction as to where they should focus their future R & D efforts o
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A High Throughput Approach for Metabolite Profiling and Characterization Using the LXQ Linear Ion Trap Mass Spectrometer
Thermo Fisher Scientific
A high throughput LC-MS/MS approach has been developed for metabolic profiling using the LXQ linear ion trap mass spectrometer. The rapid LC-MS/MS method made use of Data-Dependent™ acquisitions to study known metabolites and to uncover unexpected metabolites. The identification and characterization of glyburide along with 19 metabolites was accomplished in a single LC run of approximately three minutes using the fast cycle time, high sensitivity and excellent spectral quality of this instrument
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