BMG LABTECH

Cellular Dynamics International and Roche Expand Existing Cardiotoxicity Screening Agreement
The two-year collaboration aims to enhance drug safety testing in order to bring promising therapies to patients.

Scientists Kill Cancer Cells With "Trojan Horse"
New therapy combats cancer, using a bacterially-derived nano cell to penetrate and disarm the cancer cell before a second nano cell kills it with chemotherapy drugs.

Drug Discovery Unit, University of Dundee, and DNDi Collaborate to Identify Drug Candidates to Treat Visceral Leishmaniasis
The £1.8m collaboration focuses on the discovery and development of affordable and effective therapies for the disease.

FDA's Current Ability to Regulate Genetic Testing is Problematic, FDLI-AAAS Colloquium Attendees Say
Personalized medicine stakeholders’ meeting elicits varying perspectives.

Gene Expression Findings a Step toward Better Classification and Treatment of Juvenile Arthritis
Findings could enable clinicians to target more aggressive treatment to children at risk of more severe arthritis.

Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy

The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.

Anti-inflammatory activity of Dalbergia sissoo Roxb. heart-wood
L. M. College of Pharmacy

The heart-wood of Dalbergia sissoo Roxb. is reported to be used in traditional medicinal practices, of which anti-inflammatory is one. The present work evaluates the effect of the heart-wood extract on the carrageenan induced rat paw edema. The drug was found to be active at lowest of 3 doses tried. the drug can be said to posses anti-inflamatory activity but needs further evaluation of discover the pathway of the same.

Senior Director ADME
The RSA Group
Hatfield, Herts, UK

Mass Spectometry Scientist
Roswell Park Cancer Institute
Buffalo, NY, USA

Principal HTS Scientist
St. Jude Childrens Research Hospital
Memphis, TN, USA


Target Discovery World Congress, South San Francisco, CA, USA
04 August 2009 - 05 August 2009

Target Discovery World Congress will be a meeting focusing on the research looking to find new potential drugs for development. The topics will include presentations on the latest in screening platforms and new methods such as those in High Content and Label-Free Screening and will also focus on the work being done looking for new drug targets in some of the major protein families including Ion Channels, GPCRs, Protein Kinases, Nuclear Receptors and the Ubiquitin Pathway.

Molecular Diagnostics World Congress, South San Franscisco, CA, USA
06 August 2009 - 07 August 2009

Welcome to the 2nd Molecular Diagnostics World Congress, this year's event will take place at the South San Francisco Conference Center.

Drug Delivery, London, England
02 September 2009 - 02 September 2009

The summit includes three one-day symposia on the following subjects: Delivery of Small Molecules & Nucleic Acids, Delivery of Macromolecules and Formulation & Solubility
  


Retigabine and Therapeutic Indications of Activating Neuronal KCNQ Voltage-Gated Potassium Ion Channels

Jim Wu, Head of Discovery Biology, Roche R&D Center, speaking at Ion Channel Targets 2008


Hypertension in P2Y2 Receptor-Deficient Mice is Caused by Constitutive Activation of ENaC

James Stockand, Associate Professor, University of Texas Health Science Center at Houston, speaking at Ion Channel Targets 2008

Toxicity Screening 2009 Market Report
Published February 2009

This is the latest and most up-to-date Toxicity Screening Market Analysis Report from Select Biosciences. This comprehensive report provides a qualitative and quantitative analysis of the toxicity screening space, market metrics, and thorough bottom-up based market trends obtained via detailed market surveys administered by Select Biosciences to a worldwide industry participant pool.

Label Free Binding Analysis Trends 2008 Market Report
HTStec

The study was initiated to gain a better understanding of the market requirements for label free technologies used in the study of biomolecular interactions. The aims were to document the main challenges faced by groups applying binding analysis; their status with regard to the search for new technology; to understand their willingness to change workflows and to identify unmet needs.

A High Throughput Approach for Metabolite Profiling and Characterization Using the LXQ Linear Ion Trap Mass Spectrometer
Thermo Fisher Scientific

A high throughput LC-MS/MS approach has been developed for metabolic profiling using the LXQ linear ion trap mass spectrometer. The rapid LC-MS/MS method made use of Data-Dependent™ acquisitions to study known metabolites and to uncover unexpected metabolites. The identification and characterization of glyburide along with 19 metabolites was accomplished in a single LC run of approximately three minutes using the fast cycle time, high sensitivity and excellent spectral quality of this instrument